[Relationship between body composition and the risk of non-communicable chronic diseases in active older women from Chillán (Chile).] / Relación entre la composición corporal y el riesgo de enfermedades crónicas no transmisibles en mujeres mayores activas de Chillán (Chile).

OBJECTIVE: In Chile, the elderly represent 18% of the population. In women, the aging process impacts body composition, in addition to the coexistence of other pathologies such as chronic noncommunicable diseases (NCDs). The aim of the study was to relate body composition to the presence of chronic noncommunicable diseases in active older women in the city of Chillán. METHODS: The sample consisted of 284 women belonging to senior centers in Chillán. Body composition was determined by bioimpedanciometry. Sociodemographic information, prevalent pathologies, geriatric syndromes and physical activity were determined by means of a validated questionnaire. Data were analyzed with descriptive and inferential statistics in STATA 15.0 software with an α<0.05. RESULTS: Of the sample, 63% were under seventy-five years of age, 77.5% had less than twelve years of schooling, the predominant socioeconomic level was low, and the poor perception of health was mainly referred to as well as the use of regular medication. Arterial hypertension (AHT) and hypercholesterolemia were prevalent with 70.4% and 48.2% respectively. Body mass index (BMI) was 29.7±4.8 and 71.8% had excess malnutrition. The group older than seventy-five years presented more body fat (BMF) and extracellular water (ECW). AHT was related to higher BMI, TGM, MBC (Mean Arm Circumference), PC (Calf Circumference) and ECW (p<0.05), while Diabetes mellitus was related to BMI and MBC. CONCLUSIONS: Hypertension is the most frequent pathology and is related to higher BMI, MGT, CMB, CP and ECW, followed by DM2 which is related to BMI and CMB.

OBJETIVO: En Chile, las personas mayores representan el 18% de la población. En mujeres, el proceso de envejecimiento impacta sobre la composición corporal, además de coexistir con otras patologías como enfermedades crónicas no transmisibles (ECNT). El objetivo del estudio fue relacionar la composición corporal con la presencia de enfermedades crónicas no transmisibles en mujeres mayores activas de la ciudad de Chillán. METODOS: La muestra quedó compuesta por 284 mujeres pertenecientes a centros de adultos mayores de Chillán. La composición corporal se determinó por bioempidenciometría. La información sociodemográfica, las patologías prevalentes, los síndromes geriátricos y la actividad física se recabó mediante cuestionario validado. Los datos se analizaron con estadística descriptiva e inferencial en el software STATA 15.0 con un α<0,05. RESULTADOS: De la muestra, el 63% tenía menos de setenta y cinco años, 77,5% presentó una escolaridad por debajo de los doce años, el nivel socioeconómico predominante fue bajo, y la mala percepción de salud fue referida mayoritariamente al igual que el uso regular de medicamentos. La hipertensión arterial (HTA) y la hipercolesterolemia fueron prevalentes con un 70,4% y un 48,2%, respectivamente. El Índice de masa corporal (IMC) fue de 29,7±4,8 y el 71,8% tenía malnutrición por exceso. El grupo mayor a setenta y cinco años presentó más grasa corporal (MGT) y agua extracelular (AEC). La HTA se relacionó con mayor IMC, MGT, CMB (Circunferencia Media del Brazo), CP (Circunferencia de Pantorrilla) y AEC (p<0,05), mientras que la Diabetes mellitus con el IMC y la CMB. CONCLUSIONES: La hipertensión es la patología más frecuente y se relaciona con mayor IMC, MGT, CMB, CP y AEC, siguiéndole la DMII, que se relaciona con el IMC y la CMB.

Alta prevalencia de malnutrición por déficit e inseguridad alimentaria en pm institucionalizadas en establecimientos de larga estadía (ELEAM) de las comunas de Chillán y Chillán Viejo, Chile

El acceso y disponibilidad a alimentos seguros y nutritivos, es prioritario para obtener una buena nutrición, con el fin de mejorar la salud y calidad de vida de las personas mayores (PM). El objetivo del estudio fue determinar la prevalencia de malnutrición por déficit e inseguridad alimentaria en PM institucionalizadas en ELEAM, de las comunas de Chillán y Chillán Viejo, Región de Ñuble. Estudio descriptivo que incluyó a 63 personas de 65-96 años, residentes en 7 ELEAM de las comunas de Chillán y Chillán Viejo que aceptaron participar del estudio. Se evaluó el estado nutricional mediante Índice de Masa Corporal (IMC), circunferencia braquial (CB), perímetro de pantorrilla (PP); y se aplicó Escala de Seguridad Alimentaria adaptada y validada. La información se analizó con estadística descriptiva uni y bivariada según tipo de variables. El grupo estuvo conformado mayoritariamente por mujeres (74,6%). La situación nutricional más prevalente fue la malnutrición por déficit (42,9%), seguida por el estado nutricional normal (31,7%). La CB mostró valores promedios de 26,9±3,5 cm en las mujeres y de 26,8±4,5 cm en los hombres; según PP el 39,6% presentó déficit de masa muscular. La seguridad alimentaria estuvo presente en el 20,6% de los encuestados y la inseguridad alimentaria en el 79,3%. Se concluye que las PM pertenecientes a los ELEAM estudiados, presentaron mayoritariamente malnutrición por déficit, e inseguridad alimentaria, lo que no contribuye a una mejor salud del grupo estudiado.

Access to and availability of sufficient, safe, and nutritious food is a priority for quality nutrition for the health and quality of life of the elderly. The objective of this study was to determine the prevalence of undernutrition due to food deficit and insecurity in institutionalized elderly individuals in long-term care facilities (ELEAM) in the communes of Chillán and Chillán Viejo, Ñuble Region, Chile. This descriptive study included 63 individuals aged 65-96 residing in seven ELEAM in the communes of Chillán and Chillán Viejo that accepted to participate. Nutritional status was evaluated by Body Mass Index (IMC), mid-arm circumference (MAC), and calf perimeter (CP); and an adapted and validated Food Security Scale was applied. The information was analyzed using univariate and bivariate descriptive statistics by type of variable. The group consisted mainly of women (74.6%). The most prevalent nutritional status was deficit malnutrition (42.9%), followed by normal nutritional status (31.7%). CB showed mean values of 26.9 ± 3.5 cm in women and 26.8± 4.5 cm in men; according to CP, 39.6% presented a deficit of muscular mass. Food security and insecurity were present in 20.6% and 79.3% of the respondents, respectively. It was concluded that the elderly belonging to the ELEAMs studied presented mostly deficit malnutrition, and food insecurity, which does not contribute to the better health of the group studied.

Relación entre la composición corporal y el riesgo de enfermedades crónicas no transmisibles en mujeres mayores activas de Chillán (Chile) / Relationship between body composition and the risk of non-communicable chronic diseases in active older women from Chillán (Chile)

FUNDAMENTOS: En Chile, las personas mayores representan el 18% de la población. En mujeres, el proceso de envejecimientoimpacta sobre la composición corporal, además de coexistir con otras patologías como enfermedades crónicas no transmisibles(ECNT). El objetivo del estudio fue relacionar la composición corporal con la presencia de enfermedades crónicas no transmisibles enmujeres mayores activas de la ciudad de Chillán. MÉTODOS: La muestra quedó compuesta por 284 mujeres pertenecientes a centros de adultos mayores de Chillán. La composi-ción corporal se determinó por bioempidenciometría. La información sociodemográfica, las patologías prevalentes, los síndromesgeriátricos y la actividad física se recabó mediante cuestionario validado. Los datos se analizaron con estadística descriptiva einferencial en el softwareSTATA 15.0 con un α<0,05. RESULTADOS: De la muestra, el 63% tenía menos de setenta y cinco años, 77,5% presentó una escolaridad por debajo de los doceaños, el nivel socioeconómico predominante fue bajo, y la mala percepción de salud fue referida mayoritariamente al igual que eluso regular de medicamentos. La hipertensión arterial (HTA) y la hipercolesterolemia fueron prevalentes con un 70,4% y un 48,2%,respectivamente. El Índice de masa corporal (IMC) fue de 29,7±4,8 y el 71,8% tenía malnutrición por exceso. El grupo mayor a setentay cinco años presentó más grasa corporal (MGT) y agua extracelular (AEC). La HTA se relacionó con mayor IMC, MGT, CMB (Circun-ferencia Media del Brazo), CP (Circunferencia de Pantorrilla) y AEC (p<0,05), mientras que la Diabetes mellitus con el IMC y la CMB. CONCLUSIONES: La hipertensión es la patología más frecuente y se relaciona con mayor IMC, MGT, CMB, CP y AEC, siguiéndole laDMII, que se relaciona con el IMC y la CMB.

BACKGROUND: In Chile, the elderly represent 18% of the population. In women, the aging process impacts body composition, inaddition to the coexistence of other pathologies such as chronic noncommunicable diseases (NCDs). The aim of the study was torelate body composition to the presence of chronic noncommunicable diseases in active older women in the city of Chillán. METHODS: The sample consisted of 284 women belonging to senior centers in Chillán. Body composition was determined by bioim-pedanciometry. Sociodemographic information, prevalent pathologies, geriatric syndromes and physical activity were determined bymeans of a validated questionnaire. Data were analyzed with descriptive and inferential statistics inSTATA 15.0 software with an α<0.05. RESULTS: Of the sample, 63% were under seventy-five years of age, 77.5% had less than twelve years of schooling, the predomi-nant socioeconomic level was low, and the poor perception of health was mainly referred to as well as the use of regular medication.Arterial hypertension (AHT) and hypercholesterolemia were prevalent with 70.4% and 48.2% respectively. Body mass index (BMI) was29.7±4.8 and 71.8% had excess malnutrition. The group older than seventy-five years presented more body fat (BMF) and extracellularwater (ECW). AHT was related to higher BMI, TGM, MBC (Mean Arm Circumference), PC (Calf Circumference) and ECW (p<0.05), whileDiabetes mellitus was related to BMI and MBC. CONCLUSIONS: Hypertension is the most frequent pathology and is related to higher BMI, MGT, CMB, CP and ECW, followed by DM2which is related to BMI and CMB.(AU)

Predictive Equations Overestimate Resting Metabolic Rate in Young Chilean Women with Excess Body Fat.

Underestimating/overestimating resting metabolic rate (RMR) affects energy prescription. The objective was to compare RMR by indirect calorimetry (RMR IC) and RMR estimated by predictive equations in women with excess body fat. This was an analytical cross-sectional study with 41 women aged 18-28 with overnutrition according to body composition. The RMR IC was measured and RMR estimated using the FAO/WHO/UNU (1985), FAO/WHO/UNU (2004), Harris-Benedict, and Mifflin-St Jeor equations. The percentage of adequacy (90-110%), overestimation (>110%), and underestimation (<90%) were evaluated for RMR IC. Data were described by percentiles because of non-normal distribution according to the Shapiro-Wilk test. The Kruskal-Wallis test and Bland-Altman analysis were applied at a significance level of α < 0.05. The RMR IC was 1192 and 1183 calories/day (p = 0.429) in women with obesity and overweight, respectively. The FAO/WHO/UNU (1985), FAO/WHO/UNU (2004), Harris-Benedict, and Mifflin-St Jeor equations overestimated the RMR IC by 283.2, 311.2, 292.7, and 203.0 calories/day and by 296.7, 413.8, 280.0, and 176.6 calories/day for women with overweight and obesity (p < 0.001), respectively. The Harris-Benedict adjusted weight (0.5) equation underestimated RMR IC by 254.7 calories/day. The predictive equations overestimated RMR IC in women with excess body fat. The Mifflin-St Jeor equation showed less overestimation and better adequacy, but was not exempt from inaccuracy.

Are Enterobacteriaceae and Enterococcus Isolated from Powdered Infant Formula a Hazard for Infants? A Genomic Analysis.

Powdered infant formulas (PIF) are the most used dietary substitutes that are used in order to supplement breastfeeding. However, PIF are not sterile and can be contaminated with different microorganisms. The objective of this study was to genomically characterize Enterobacteriaceae (ENT) and Enterococcus strains that were isolated from PIF. Strains were identified by matrix-assisted laser desorption ionization-time-of-flight mass spectrometry (MALDI-TOF MS) and whole-genome sequencing (WGS). Genomic typing, detection of virulence, and resistance profiles and genes were performed with the Ridom SeqSphere+ software; the comprehensive antibiotic resistance database (CARD) platform; ResFinder and PlasmidFinder tools; and by the disk diffusion method. Nineteen isolates from PIF were analyzed, including ENT such as Kosakonia cowanii, Enterobacter hormaechei, Franconibacter helveticus, Mixta calida, and lactic acid bacteria such as Enterococcus faecium. The strains exhibited resistance to beta-lactams, cephalosporins, and macrolides. Resistance genes such as AcrAB-TolC, marA, msbA, knpEF, oqxAB, fosA, blaACT-7, blaACT-14,qacJ, oqxAB,aac(6')-Ii, and msr(C); and virulence genes such as astA, cheB, cheR, ompA ompX, terC, ironA, acm, and efaAfm, adem were also detected. All the analyzed strains possessed genes that produced heat-shock proteins, such as IbpA and ClpL. In PIF, the presence of ENT and Enterococcus that are multiresistant to antibiotics-together with resistance and virulence genes-pose a health risk for infants consuming these food products.

Association between Homophobia and Sociodemographic Characteristics in Health Workers in Southern Chile.

Homophobic attitude in health workers is a social determinant in the health of the homosexual population because it affects healthcare and its access and equity. The objective was to determine the relationship between the level of homophobia and sociodemographic characteristics of primary health workers in southern Chile. This was an analytical cross-sectional study. The sample consisted of 491 public servants from health centers in southern Chile. The attitudes toward lesbians and gay men (ATLG) scale was applied, and a binary logistic regression model was performed to evaluate the association. The study participants were predominantly women (76.0%), under 40 years of age (63.5%), heterosexuals (93.5%), and unpartnered (68.2%) but with children (61.7%), and they also had an educational attainment ≥ 12 years (66.6%). About 87.6% of the participants held healthcare positions, and the majority were religious believers (74.3%) and had a centrist political affiliation (51.0%). Results indicated that 34% of the participants exhibited homophobic attitudes; there were statistically significant differences with respect to age, number of children, educational attainment, religion, and political affiliation (p < 0.01). These were higher in individuals ≥40 years of age, with ≥3 children, with educational attainment ≥ 12 years, holding a healthcare position, who were religious believers, and who had right-wing political affiliation.

Maternal Factors Associated with Non-Exclusive Breastfeeding in Haitian Immigrant Women in Southern Chile.

There is limited knowledge concerning factors that affect non-exclusive breastfeeding (NEBF) practices in immigrant populations, especially in Latin America. The objective of the present study was to determine the association between maternal factors and the prevalence of NEBF in Haitian immigrant women in southern Chile. This was an analytical cross-sectional study. The probabilistic sample consisted of 173 Haitian women who gave informed consent. Sociodemographic and dietary-nutritional information was collected from all participants. Bivariate (χ2) and multivariate (logistic regression) inferential statistics were applied. All analyses were performed with the STATA 16.0 statistical software, and the significance level was established as α < 0.05. The prevalence of EBF at 6 mo was 54.3%. Maternal factors associated with a lower prevalence of EBF were not having permanent residency (OR: 2.34, CI: 2.18−2.83), residency <12 months (OR: 2.23, CI: 2.09−2.78), limited knowledge of breastfeeding (OR: 1.96; CI: 1.81−2.27), and low educational attainment (OR: 1.78; CI: 1.61−2.11). The protective factors were employment (OR: 0.36, CI: 0.28−0.40), access to basic services (OR: 0.32; CI: 0.22−0.48), and Spanish proficiency (OR: 0.29; CI: 0.20−0.51). Haitian immigrant women without legal residency, recently arrived, with low educational attainment, and poor knowledge of breastfeeding have more risk of not providing exclusive breastfeeding. Targeted interventions for mothers with these risk factors may help improve EBF rates.

Predictive Equation to Estimate Resting Metabolic Rate in Older Chilean Women.

Resting metabolic rate (RMR) depends on body fat-free mass (FFM) and fat mass (FM), whereas abdominal fat distribution is an aspect that has yet to be adequately studied. The objective of the present study was to analyze the influence of waist circumference (WC) in predicting RMR and propose a specific estimation equation for older Chilean women. This is an analytical cross-sectional study with a sample of 45 women between the ages of 60 and 85 years. Weight, height, body mass index (BMI), and WC were evaluated. RMR was measured by indirect calorimetry (IC) and %FM using the Siri equation. Adequacy (90% to 110%), overestimation (>110%), and underestimation (<90%) of the FAO/WHO/UNU, Harris−Benedict, Mifflin-St Jeor, and Carrasco equations, as well as those of the proposed equation, were evaluated in relation to RMR as measured by IC. Normal distribution was determined according to the Shapiro−Wilk test. The relationship of body composition and WC with RMR IC was analyzed by multiple linear regression analysis. The RMR IC was 1083.6 ± 171.9 kcal/day, which was significantly and positively correlated with FFM, body weight, WC, and FM and inversely correlated with age (p < 0.001). Among the investigated equations, our proposed equation showed the best adequacy and lowest overestimation. The predictive formulae that consider WC improve RMR prediction, thus preventing overestimation in older women.

Malnutrición por exceso en niños de 5 a 10 años y su asociación con el estado nutricional pre y gestacional, lactancia materna y patología materna

La malnutrición por exceso es un problema de salud pública relevante, con origen multifactorial y factores asociados como el estado nutricional pregestacional (ENP), durante y post gestación, ganancia excesiva de peso (EGP) gestacional y duración de la lactancia materna. El objetivo del estudio fue evaluar la malnutrición por exceso en niños de 5 a 10 años y su asociación con el estado nutricional pre y gestacional, lactancia materna exclusiva (LME) y patologías maternas. Se realizó un estudio con 213 niños y niñas estudiantes de 5 a 10 años. Los datos biosociodemográficos se obtuvieron mediante entrevistas con las madres y datos maternos previos y el embarazo con el carné de control. El estimó estado nutricional se estimó con z-score del peso para la talla e IMC/E, según sexo. Para los análisis estadísticos se usó el software STATA 15.0. El 56% de los estudiantes tuvo malnutrición por exceso. Un 53,1% de las madres presentó malnutrición por exceso previo al embarazo que aumentó a 74,6% post gestación. El 71,4% de los niños tuvo una LME ≥6 meses. Se relacionó estadísticamente la edad materna ≥35 años (p= 0,044) y la malnutrición por exceso pregestacional (p= 0,014). La edad materna ≥35 años aumentó el riesgo de malnutrición por exceso casi dos veces (OR= 1,78; IC: 1,029-3,046), al igual que el ENP (OR= 2,11; IC: 1,193-3,693) y en patologías maternas (OR= 1,41; IC: 1, 073-2,694). En conclusión, los niños preescolares de 5 a 10 años con factores de edad materna ≥35, ENP y patologías maternas tuvieron entre 1,4 y 2,11 veces más riesgo de presentar malnutrición por exceso comparado con aquellos niños sin estos factores.

Overnutrition is a relevant public health problem with a multifactorial origin. Associated factors include maternal nutritional status before, during, and after gestation, excessive gestational weight gain, and breastfeeding duration. The objective of the study was to evaluate the association between overnutrition in children aged 5-10 years and pre- and gestational nutritional status, exclusive breastfeeding, and maternal pathologies. The study consisted of 213 schoolchildren aged 5-10 years. Bio-socio-demographic data were obtained through interviews with mothers, previous maternal data and pregnancy follow-up records. Nutritional status was measured using weight-for-height and BMI z-score by age and sex. The STATA 15.0 software was used for statistical analysis. A total of 56% of the schoolchildren had overnutrition. Meanwhile, 53.1% of the mothers demonstrated pre-pregnancy overnutrition, which increased to 74.6% post-pregnancy. It was found that 71.4% of schoolchildren had experienced exclusive breastfeeding ≥6 months. Maternal age ≥35 years (p= 0.044) and pre-gestational nutritional status (p= 0.014) were statistically related. Maternal age ≥35 years increased overnutrition by almost two-fold (OR= 1.78; IC: 1.029-3.046), as did pre-gestational nutritional status (OR= 2.11; IC: 1.193-3.693) and maternal pathologies (OR= 1.41; IC: 1.073-2.694). In conclusion, schoolchildren aged 5-10 years with mothers ≥35 years of age, who had overnutrition in the pre-gestational period, and a pathology were 1.4 to 2.44 times more at risk of developing overnutrition than children without these factors.

Association between Maternal Factors, Preterm Birth, and Low Birth Weight of Chilean Singletons.

There has been an increase in preterm (PT) births in Western countries in recent years, which is associated with low-birthweight (LBW) children. The aim of this study was to determine the association between maternal factors and PT and LBW Chilean newborns. Methods: This was an analytical cross-sectional study of a national sample of 903,847 newborns and their mothers. The newborn gestational age, birth weight, maternal age, marital status, education, employment situation, and residence were analyzed. A multivariate logistic regression model was applied (α = 0.05) (STATA v.15). The prevalence was 6.8% and 5.0% for PT and LBW, respectively. The probability of the newborns being PT and LBW was 1.18 and 1.22 times if their mothers had <12 years of education and 1.38 and 1.29 times if the mothers were ≥35 years old, respectively. Mothers with <12 years education and ≥35 years were risk factors for PT and LBW newborns. Maternal educational attainment was a protective factor for the Chilean newborns, and a maternal age ≥35 years was a risk factor for PT and LBW.

Obese Women Have a High Carbohydrate Intake without Changes in the Resting Metabolic Rate in the Luteal Phase.

Hormonal changes are caused by the menstrual cycle phases, which influence resting metabolic rate and eating behavior. The aim of the study was to determine resting metabolic rate (RMR) and its association with dietary intake according to the menstrual cycle phase in lean and obese Chilean women. This cross-sectional analytical study included 30 adult women (15 lean and 15 with obesity). Body composition was measured with a tetrapolar bioelectrical impedance meter. Nutritional status was determined by adiposity. A 24-h recall of three nonconsecutive days verifies dietary intake. The RMR was measured by indirect calorimetry. All measurements were performed in both the follicular and luteal phases of the menstrual cycle. Statistical analyses were performed with STATA software at a significance level, which was α = 0.05. The RMR (ß = 121.6 kcal/d), temperature (ß = 0.36 °C), calorie intake (ß = 317.1 kcal/d), and intake of lipids (ß = 13.8 g/d) were associated with the luteal phase in lean women. Only extracellular water (ß = 1.11%) and carbohydrate consumption (ß = 45.2 g/d) were associated in women with obesity. Lean women showed increased RMR, caloric intake, and lipid intake during the luteal phase. For women with obesity, carbohydrate intake increased but not RMR.

Association of Prematurity and Low Birth Weight with Gestational Exposure to PM2.5 and PM10 Particulate Matter in Chileans Newborns.

Fetal growth can be affected by gestational exposure to air pollution. The aim of the study was to determine the association between prematurity and low birth weight (LBW) with gestational exposure to PM2.5 and PM10 particulate matter in Chileans newborns. This cross-sectional analytical study included 595,369 newborns. Data were extracted from the live newborn records of the Chilean Ministry of Health. Sex, gestational age, birth weight, and living variables were analyzed. We used the Air Quality Information System of the Chilean Ministry of the Environment to obtain mean PM2.5 and PM10 emissions. A multivariate logistic regression model was performed with STATA 15.0 software at α < 0.05. Prevalence was 7.4% prematurity and 5.5% LBW. Mean PM2.5 and PM10 concentrations were 25.5 µg/m3 and 55.3 µg/m3, respectively. PM2.5 was associated with an increased the risk of LBW (OR: 1.031; 95%CI: 1.004−1.059) when exposure occurred in the second trimester, while PM10 affected the whole pregnancy. In addition, PM10 exposure in any gestational trimester was associated with an increased the risk of prematurity. The PM10 particulate matter was associated with both prematurity and LBW in all of the trimesters of exposure. The PM2.5 particulate matter was only associated with LBW when exposure occurred in the second gestational trimester.

Profiling the Virulence and Antibiotic Resistance Genes of Cronobacter sakazakii Strains Isolated From Powdered and Dairy Formulas by Whole-Genome Sequencing.

Cronobacter sakazakii is an enteropathogen that causes neonatal meningitis, septicemia, and necrotizing enterocolitis in preterm infants and newborns with a mortality rate of 15 to 80%. Powdered and dairy formulas (P-DF) have been implicated as major transmission vehicles and subsequently the presence of this pathogen in P-DF led to product recalls in Chile in 2017. The objective of this study was to use whole genome sequencing (WGS) and laboratory studies to characterize Cronobacter strains from the contaminated products. Seven strains were identified as C. sakazakii, and the remaining strain was Franconibacter helveticus. All C. sakazakii strains adhered to a neuroblastoma cell line, and 31 virulence genes were predicted by WGS. The antibiograms varied between strains. and included mcr-9.1 and bla CSA genes, conferring resistance to colistin and cephalothin, respectively. The C. sakazakii strains encoded I-E and I-F CRISPR-Cas systems, and carried IncFII(pECLA), Col440I, and Col(pHHAD28) plasmids. In summary, WGS enabled the identification of C. sakazakii strains and revealed multiple antibiotic resistance and virulence genes. These findings support the decision to recall the contaminated powdered and dairy formulas from the Chilean market in 2017.

Índice de alimentación saludable e indicador sodio/(potasio+calcio) en estudiantes universitarios chilenos / Healthy eating index and sodium/(potassium+calcium) indicator in Chilean university students

Resumen Introducción: Los hábitos alimentarios poco saludables de los estudiantes universitarios constituyen una preocupación importante para la atención medica-nutricional futura. Objetivo: Determinar el Índice de Alimentación Saludable (IAS) e indicador sodio/(potasio+calcio) en universitarios chilenos. Materiales y métodos: Investigación analítica, de corte transversal con una muestra no probabilística de 420 estudiantes, a quienes se aplicó encuesta de información sociodemográfica y antropométrica. Con el cuestionario de frecuencia de consumo y recordatorio de 24 horas se determinó el IAS e indicador sodio/(potasio+calcio). Se aplicó estadística descriptiva e inferencial utilizando el programa Statistical Package for the Social Sciences v22.0. Resultados: El peso, talla e Índice de Masa Corporal, presentaron diferencias estadísticamente significativas, según sexo (p<0,05). Misma situación fue encontrada en el promedio de ingesta de calorías, lípidos, carbohidratos, fibra, calcio y sodio (p<0,05). La ingesta de frutas, verduras y lácteos bajos en grasa fue mayor en mujeres (p<0,01). La mayoría de los sujetos presentaron alimentación poco saludable, siendo mayor en el caso de los hombres (p<0,05). Sólo el 6% de los hombres y 17% de las mujeres tenían una dieta cardio-protectora. Conclusiones: Los estudiantes presentan una dieta con deficiente ingesta de micronutrientes cardioprotectores, hecho que incrementa el riesgo de desarrollar enfermedades cardiovasculares.

Abstract Introduction: Unhealthy eating habits of university students constitutes an important concern for future medical and nutritional care. Objective: To determine the Healthy Eating Index (HEI) and the sodium/(potassium+calcium) indicator in Chilean university students. Materials and methods: An analytical cross-sectional research was carried out with a non-probabilistic sample of 420 students, who answered a survey covering sociodemographic and anthropometric issues. The HEI and sodium/(potassium+calcium) indicator were determined using the consumption frequency and 24-hour reminder questionnaire. A descriptive and inferential statistical analysis was applied through the SPSS (v22.0) program. Results: The weight, height and the body mass index (BMI) of the participants showed statistically significant differences according to their gender (p<0.05). A similar pattern was found in the average intake of calories, lipids, carbohydrates, fiber, calcium and sodium (p<0.05). Intake of fruits, vegetables and low-fat dairy products was higher in women (p<0.01). The majority of participating students had an unhealthy diet, with the situation being more severe in men (p<0.05). Only 6% of men and 17% of women had a cardio-protective diet. Conclusions: Students follow diets with a deficient intake of cardio-protective micronutrients, which increases the risk of developing cardiovascular diseases.

Estrés académico y estrategias de afrontamiento en estudiantes de carreras de salud de Santiago de Chile / Academic stress and coping strategies in students of health degrees in Santiago de Chile

RESUMEN Fundamento: el stress académico en los estudiantes universitarios puede desencadenar manifestaciones en el orden físico, psicológico y social. Objetivo: determinar el estrés académico y las estrategias de afrontamiento en estudiantes de carreras de salud en Santiago de Chile. Métodos: se realizó un estudio transversal-analítico en una institución de educación superior privada de Santiago de Chile durante el año 2019. Se emplearon los instrumentos de Estrés Académico modificado y la Escala de Afrontamiento del Estrés Académico a la muestra de estudiantes. Se utilizó estadística descriptiva e inferencial, utilizando ANOVA (one-way), test de posthoc de Tukey y Chi2. La significancia se estableció en α<0,05 y los análisis se realizaron con el software STATA 15.0. Resultados: más del 70 % de la muestra se encontraba en un nivel socioeconómico medio-bajo. La situación generadora de estrés predominante estuvo referida a la sobrecarga de trabajo, la cual fue diferente entre los estudiantes de Enfermería (4,1±0,7) en comparación con los de las otras carreras (p=0,032). Ellos presentaron principalmente reacciones físicas ante las situaciones del estrés académico (p=0,024) mientras que los de Terapia Ocupacional tuvieron mayormente reacciones psicológicas (p=0,21). Estos últimos refirieron la revaluación positiva como estrategia de afrontamiento, mientras que el resto de las carreras prefieren la búsqueda de apoyo (p=0.032). Conclusiones: se determinó el estrés académico y sus estrategias de afrontamiento en estudiantes de carreras de salud en Santiago de Chile, quienes identificaron la sobrecarga de trabajo como su génesis sin presentar diferencias entre programas de estudio, pero sí en su afrontamiento.

ABSTRACT Background: academic stress in university students can trigger manifestations in the physical, psychological and social order. Objective: to determine academic stress and coping strategies in students of health degrees in Santiago de Chile. Methods: a cross-sectional-analytical study was carried out in a private higher education institution in Santiago de Chile during 2019. The modified Academic Stress instruments and the Academic Stress Coping Scale were applied to the sample of students. Descriptive and inferential statistics were used, using ANOVA (one-way), Tukey's posthoc test and Chi2. Significance was established at α <0.05 and analyzes were performed with the STATA 15.0 software. Resultados: más del 70 % de la muestra se encontraba en un nivel socioeconómico medio-bajo. La situación generadora de estrés predominante estuvo referida a la sobrecarga de trabajo, la cual fue diferente entre los estudiantes de Enfermería (4,1±0,7) en comparación con los de las otras carreras (p=0,032). Ellos presentaron principalmente reacciones físicas ante las situaciones del estrés académico (p=0,024) mientras que los estudiantes Terapia Ocupacional tuvieron principalmente reacciones psicológicas (p=0,21). Estos últimos refirieron la revaluación positiva como estrategia de afrontamiento, mientras que el resto de las carreras prefieren la búsqueda de apoyo (p=0.032). Conclusiones: se determinó el estrés académico y sus estrategias de afrontamiento en estudiantes de carreras de salud en Santiago de Chile, quienes identificaron la sobrecarga de trabajo como su génesis sin presentar diferencias entre programas de estudio, pero sí en su enfrentamiento.

Relación entre contaminación atmosférica y consultas por enfermedades respiratorias en atención primaria de urgencia / Relationship between air pollution and respiratory disease consultations in primary emergency care

Resumen La presente investigación indaga la relación entre los niveles de contaminación ambiental por material particulado 2,5 y consultas respiratorias según tipo de enfermedad respiratoria y edad de los usuarios que consultaron en los Servicios de Atención Primaria de Urgencia de 2 comunas de la Región de Ñuble, Chile, entre los años 2016 y 2017 mediante un diseño de tipo ecológico. La unidad de análisis correspondió a medias agrupadas (promedios) de consultas diarias por enfermedades respiratorias y de concentración de material particulado 2,5. Los análisis estadísticos utilizados fueron Anova, test estadístico Dickey-Fuller, análisis inferencial basado en correlación de Spearman y Cross-Correlation. Se observó una correlación positiva entre los niveles de contaminación ambiental y consultas por enfermedades respiratorias registrados al día siguiente y al noveno día posterior a un episodio de emergencia ambiental. Desde la entrada en vigencia del Plan de Prevención y Descontaminación Atmosférica no se observan diferencias significativas en las concentraciones de MP2,5 entre los años 2016 y 2017. Los mayores niveles de contaminación ambiental se concentran entre los meses de abril a septiembre. En conclusión, existe relación entre los niveles de contaminación ambiental por MP2,5 con el número de consultas por enfermedades respiratorias y la edad de los usuarios.

The present investigation inquires the relation between the levels of environmental pollution by air borne particulate matter 2,5 and respiratory-related consultatons according to type of respiratory disease and age of the users who were admitted in the Primary Healthcare Emergency Services in two communes in Chile's Ñuble Region, between 2016 and 2017 through an ecological design. The unit of analysis corresponded to pooled means (averages) of daily consultations for respiratory diseases and concentration of particulate matter 2.5. The statistical methods used were: Anova, statistical test Dickey-Fuller, inferential analysis based on Spearman's correlation and Cross-Correlation. A positive correlation was observed between environmental pollution and consultations related to respiratory diseases recorded the next day and the ninth day after an environmental emergency episode. Since the entry into force of the Atmospheric Prevention and Decontamination Plan, no significant differences have been observed in the concentrations of PM2.5 between 2016 and 2017. The highest levels of environmental pollution are concentrated between the months of April to September. In conclusion, there is a relation between the levels of environmental pollution by PM2.5, the number of respiratory diseases consultatons and the age of users.

Ingesta alimentaria y presbifagia en adultos mayores activos de la comunidad de Chillán, Chile / Food intake and presbyphagia in active elderly adults in Chillán, Chile

RESUMEN El propósito del presente estudio fue determinar la prevalencia de presbifagia en adultos mayores que viven en la comunidad y estudiar el estado nutricional e ingesta alimentaria. Material y métodos: Estudio de caso-control con personas mayores de 65 años, pertenecientes a clubes de adultos mayores de Chillán, Chile. La ingesta alimentaria se evaluó a través de la encuesta de tendencia de consumo cuantificada y encuesta de modificación alimentaria creada y validada para este estudio. La presencia de presbifagia se diagnosticó mediante el cuestionario EAT-10 y el diagnóstico de disfagia por MECV-V realizado por fonoaudiólogo. El estado nutricional se evaluó a través del índice de masa corporal. Resultados: La prevalencia de presbifagia fue de 29,5% y disfagia 14,5%. El 74% de los adultos mayores con presbifagia tenía malnutrición por exceso versus 48% de los con disfagia, el 55,5% tenía un cumplimiento insuficiente de energía, situación que no coincide con el estado nutricional predominante de malnutrición por exceso. Las calorías consumidas fueron en base a carbohidratos y proteínas. Tenían una baja ingesta de agua, fibra, calcio y vitamina D y alto consumo de sodio. Los adultos mayores con disfagia demoran más tiempo en comer y han dejado de consumir alimentos que dificultan la deglución como frutas, carnes y arroz. Conclusión: La prevalencia de adultos mayores que viven en la comunidad con presbifagia fue de 29,5%, con malnutrición por exceso en el 74%, para facilitar el proceso deglutorio los adultos mayores con disfagia realizan modificaciones alimentarias a los sólidos.

ABSTRACT The purpose of the present study was to determine the prevalence of presbyphagia in community-living elderly persons and to study nutritional status and dietary intake. Material and methods: We conducted a case-control study with persons over 65 years of age, belonging to clubs for the elderly in Chillán, Chile. Dietary intake was evaluated through a food frequency questionnaire and food modification survey created and validated for this study. Presbyphagia was diagnosed by means of the EAT-10 questionnaire and dysphagia by a speech therapist with MECV-V. The nutritional status was evaluated through the body mass index. Results: The prevalence of presbyphagia was 29.5% and dysphagia 14.5%. 74% of those with presbyphagia had excess malnutrition versus 48% of those with dysphagia, 55.5% had insufficient energy compliance, a situation that does not coincide with the prevailing nutritional status of excess malnutrition. The calories consumed were based on carbohydrates and proteins. They had a low intake of water, fiber, calcium and vitamin D and high sodium in-take. Elderly persons with dysphagia took longer to eat and reported having stopped eating foods difficult to swallow such as fruits, meats and rice. Conclusion: The prevalence of community-living elderly persons with presbyphagia was 29.5% and, among those with presbyphagia, 74% had excess malnutrition. To facilitate the swallowing process, active elderly persons with dysphagia make food modifications to solid food intake.

Association between high pre-pregnancy body mass index, excess gestational weight gain, and poor breastfeeding with overweight in 3-4-year-old Chilean children.

OBJECTIVE: The aim of this study was to determine the association between prepregnancy body mass, gestational weight gain, and inadequate breastfeeding (BF) with overweight in Chilean children ages 3 to 4 y. METHODS: This was an analytical and cross-sectional study with 560 participants. Age, residence, BF, and weight gain information were collected from child care records. The children's nutritional status (NS) was determined according to the weight-for-height z-score for sex. Bivariate relationships were evaluated by the χ2 test, and a multivariate logistic regression model was applied with the Stata version 15 software at α < 0.05. RESULTS: Prepregnancy NS values were 37% normal and 63% overweight. Excess weight gain occurred in 75% of the mothers. The children's NS was related to the duration of BF (P = 0.002), prepregnancy NS (P = 0.002), and weight gain (P = 0.004). When adjusting the logistic regression model for sex and maternal age, the overweight prepregnancy NS increased up to twice the risk for OW in children (odds ratio [OR], 2; 95% confidence interval [CI], 1.3-4.1), as well as excess weight gain (OR, 2.3; 95% CI, 1.5-5.9), and non-exclusive BF (OR, 2.4; 95% CI, 1.3-4.4). CONCLUSION: Children showing risk factors such as non-exclusive BF, prepregnancy NS with overweight, and excess gestational weight gain faced between 2 and 2.4 times more risk for overweight than children without these factors.

Problemas ortográficos en estudiantes chilenos de ciclo inicial pertenecientes a carreras de la salud / Spelling problems in Chilean students of initial cycle belonging to health degrees

RESUMEN Fundamento: las normas ortográficas resultan importantes en todo ámbito de vida, especialmente durante la formación profesional. Objetivo: caracterizar los problemas ortográficos en estudiantes chilenos de ciclo inicial pertenecientes a carreras de la salud. Métodos: estudio no experimental, descriptivo y de corte transversal. Se aplicaron métodos teóricos y como empírico: la revisión de 104 narraciones escritas por los sujetos en estudio, de las especialidades de Nutrición, Kinesiología y Fonoaudiología. Las categorías de análisis resultaron de una adaptación de las aplicadas por Sotomayor et al. (2013). A partir de ellas se evaluaron la acentuación, uso de c/s/z/b/v/h, omisión e hipo/hipersegmentación. Los datos se expresaron en frecuencias absolutas y porcentuales. Resultados: en general se observó que los estudiantes comparten valores similares en cuanto a los errores más frecuentes; en la acentuación de palabras predominaron los cometidos en las agudas en más de la mitad de los muestreados, mientras los menos frecuentes se correspondieron con la tilde diacrítica; la menor frecuencia de faltas estuvo en la segmentación. Los estudiantes de Nutrición aportaron el mayor porciento de vocablos escritos incorrectamente. Conclusiones: el diagnóstico realizado permitió caracterizar la prevalencia de errores ortográficos consumados por los sujetos en estudio. Este constituye el primer estudio realizado con universitarios chilenos de ciencias de la salud. Se hace necesario profundizar en estas investigaciones para generar estrategias contextualizadas con el propósito de minimizar la frecuencia de errores o erradicar esta deficiencia.

ABSTRACT Background: spelling rules are important in all spheres of life, especially during professional training. Objective: to characterize the spelling problems in Chilean students of the initial cycle belonging to health degrees. Methods: non-experimental, descriptive and cross-sectional study. Theoretical and empirical methods were applied: the review of 104 narratives written by the subjects under study, of the specialties of Nutrition, Kinesiology and Phonoaudiology. The analysis categories resulted from an adaptation of those applied by Sotomayor et al. (2013). From them, stress, use of c/s/z/b/v/h, omission and hypo/hyper-segmentation were evaluated. Data were expressed in absolute and percentage frequencies. Results: in general it was observed that students share similar values regarding the most frequent errors; in the stressing of words, those committed in the last syllable predominated in more than half of the sampled ones, while the less frequent ones corresponded with the diacritical accent; the lowest frequency of faults was in the segmentation. Nutrition students contributed with the highest percentage of incorrectly written words. Conclusions: the diagnosis made allowed to characterize the prevalence of spelling errors made by the subjects under study. This constitutes the first study carried out with Chilean university students of health sciences. It is necessary to deepen these investigations to generate contextualized strategies with the purpose of minimizing the frequency of errors or eradicating this deficiency.